In recognition of the Society’s 125th anniversary, and in acknowledgment of the critical role played by the APS journals in the Society’s legacy, Thomson Reuters, which produces the Journal Citation Reports database, including journal Impact Factors, was asked to identify the most highly cited articles since 1900. The Society therefore presents here the top ten cited articles for each of our journals for the following time periods: 1900-1924; 1925-1949; 1950-1959; 1960-1969; 1970-1979; 1980-1989; 1990-1999; and 2000-2011. [more]
American Journal of Physiology
A study of the adrenotropic receptors
Am J Physiol 153: 586-600, 1948.
Hamilton WF, Moore JW, Kinsman JM, Spurling RG.
Studies on the circulation IV. Further analysis of the injection method, and of changes in hemodynamtcs under physiological and pathological conditions
Am J Physiol 99: 534-551, 1932.
Tennant R, Wiggers CJ.
The effect of coronary occlusion on myocardial contraction
Am J Physiol 112: 351-361, 1935.
Kety SS, Schmidt CF.
The determination of cerebral blood flow in man by the use of nitrous oxide in low concentrations
Am J Physiol 143: 53-66, 1945.
Conduction velocity and diameter of nerve fibers
Am J Physiol 127: 131-139, 1939.
Pappenheimer JR, Sotorivera A.
Effective osmotic pressure of the plasma proteins and other quantities associated with the capillary circulation in the hindlimbs of cats and dogs
Am J Physiol 152: 471-491, 1948.
Cournand A, Motley HL, Werko L, Richards DW.
Physiological studies of the effects of intermittent positive pressure breathing on cardiac output in man
Am J Physiol 152: 162-174, 1948.
Ivy AC, Oldberg E.
A hormone mechanism for gall-bladder contraction and evacuation
Am J Physiol 86: 599-613, 1928.
Fahraeus R, Lindqvist T.
The viscosity of the blood in narrow capillary tubes
Am J Physiol 96: 562-568, 1931.
The effect of changes in the calcium content of the cerebrospinal fluid on spinal reflex activity in the dog
Am J Physiol 131: 67-72, 1940.
Body size and metabolic rate
Physiol Rev 27: 511-541, 1947.
The suspension stability of the blood
Physiol Rev 9: 241-274, 1929.
The biological significance of hyaluronic acid and hyaluronidase
Physiol Rev 27: 335-359, 1947.
Effects of oxygen at increased pressure
Physiol Rev 25: 1-147, 1945.
The nutritive significance of the amino acids
Physiol Rev 18: 109-136, 1938.
Organization for physiological homeostasis
Physiol Rev 9: 399-431, 1929.
Transport of ions across cellular membranes
Physiol Rev 29: 127-155, 1949.
Neural control of the pituitary gland
Physiol Rev 28: 139-179, 1948.
Chambers R, Zweifach BW.
Intercellular cement and capillary permeability
Physiol Rev 27: 436-463, 1947.
Madden SC, Whipple GH.
Plasma proteins: Their source, production and utilization
Physiol Rev 20: 194-217, 1940.
Journal of Neurophysiology
Spreading depression of activity in the cerebral cortex
J Neurophysiol 7: 359-390, 1944.
Magoun HW, Rhines R.
An inhibitory mechanism in the bulbar reticular formation
J Neurophysiol 9: 165-171, 1946.
Toman JEP, Swinyard EA, Goodman LS.
Properties of maximal seizures, and their alteration by anticonvulsant drugs and other agents
J Neurophysiol 9: 231-239, 1946.
Influence of discharge of motoneurons upon excitation of neighboring motoneurons
J Neurophysiol 4: 167-183, 1941.
Snider RS, Stowell A.
Receiving areas of the tactile, auditory, and visual systems in the cerebellum
J Neurophysiol 7: 331-357, 1944.
Tonic and reflex functions of medullary sympathetic cardiovascular centers
J Neurophysiol 9: 205-217, 1946.
Neuron patterns controlling transmission of ipsilateral hind limb reflexes in cat
J Neurophysiol 6: 293-315, 1943.
Hypothalamic regulation of sleep in rats - an experimental study
J Neurophysiol 9: 285-316, 1946.
Central effects of centripetal impulses in axons of spinal ventral roots
J Neurophysiol 9: 191-204, 1946.
Galambos R, Davis H.
The response of single auditory-nerve fibers to acoustic stimulation
J Neurophysiol 6: 39-57, 1943.
Journal of Applied Physiology
Analysis of tissue and arterial blood temperatures in the resting human forearm
J Appl Physiol 1: 93-122, 1948.
Riley RL, Cournand A.
Ideal alveolar air and the analysis of ventilation perfusion relationships in the lungs
J Appl Physiol 1: 825-847, 1949.
Lung function studies. 3. Uneven pulmonary ventilation in normal subjects and in patients with pulmonary disease
J Appl Physiol 2: 283-299, 1949.
Fallacy of per-weight and per-surface area standards, and their relation to spurious correlation
J Appl Physiol 2: 1-15, 1949.
Pollack AA, Wood EH.
Venous pressure in the saphenous vein at the ankle in man during exercise and changes in posture
J Appl Physiol 1: 649-662, 1949.
Hellems HK, Haynes FW, Dexter L.
Pulmonary capillary pressure in man
J Appl Physiol 2: 24-29, 1949.
Bazett HC, Love L, Newton M, Eisenberg L, Day R, Forster R.
Temperature changes in blood flowing in arteries and veins in man
J Appl Physiol 1: 3-19, 1948.
Taylor HL, Henschel A, Brozek J, Keys A.
Effects of bed rest on cardiovascular function and work performance
J Appl Physiol 2: 223-239, 1949.
Rahn H, Fenn WO, Otis AB.
Daily variations of vital capacity, residual air, and expiratory reserve including a study of the residual air method
J Appl Physiol 1: 725-736, 1949.
Amberson WR, Jennings JJ, Rhode CM.
Clinical experience with hemoglobin-saline solutions
J Appl Physiol 1: 469-489, 1949.