In recognition of the Society’s 125th anniversary, and in acknowledgment of the critical role played by the APS journals in the Society’s legacy, Thomson Reuters, which produces the Journal Citation Reports database, including journal Impact Factors, was asked to identify the most highly cited articles since 1900. The Society therefore presents here the top ten cited articles for each of our journals for the following time periods: 1900-1924; 1925-1949; 1950-1959; 1960-1969; 1970-1979; 1980-1989; 1990-1999; and 2000-2011. [more]
American Journal of Physiology
Sarnoff SJ, Braunwald E, Welch GH, Case RB, Stainsby WN, Macruz R.
Hemodynamic determinants of oxygen consumption of the heart with special reference to the tension-time index
Am J Physiol 192: 148-156, 1958.
Regional blood flow by fractional distribution of indicators
Am J Physiol 193: 161-168, 1958.
Pappenheimer JR, Renkin EM, Borrero LM.
Filtration, diffusion and molecular sieving through peripheral capillary membranes a contribution to the pore theory of capillary permeability
Am J Physiol 167: 13-46, 1951.
Steele R, Wall JS, Debodo RC, Altszuler N.
Measurement of size and turnover rate of body glucose pool by the isotope dilution method
Am J Physiol 187: 15-24, 1956.
Amdur MO, Mead J.
Mechanics of respiration in unanesthetized guinea pigs
Am J Physiol 192: 364-368, 1958.
Cross RJ, Taggart JV.
Renal tubular transport - accumulation of p-aminohippurate by rabbit kidney slices
Am J Physiol 161: 181-190, 1950.
Transport of potassium-42 from blood to tissue in isolated mammalian skeletal muscles
Am J Physiol 197: 1205-1210, 1959.
Gottschalk CW, Mylle M.
Micropuncture study of the mammalian urinary concentrating mechanism - evidence for the countercurrent hypothesis
Am J Physiol 196: 927-936, 1959.
On the physical equilibrium of small blood vessels
Am J Physiol 164: 319-329, 1951.
Bennett HS, Luft JH, Hampton JC.
Morphological classifications of vertebrate blood capillaries
Am J Physiol 196: 381-390, 1959.
Cerebral blood flow and oxygen consumption in man
Physiol Rev 39: 183-238, 1959.
Passage of molecules through capillary walls
Physiol Rev 33: 387-423, 1953.
Keys A, Brozek J.
Body fat in adult man
Physiol Rev 33: 245-325, 1953.
Effect of hormones on lymphatic tissue
Physiol Rev 32: 379-401, 1952.
The adrenal cortex and homeostasis
Physiol Rev 30: 241-320, 1950.
Relation of structure to function of the tissues of the wall of blood vessels
Physiol Rev 34: 619-642, 1954.
Fredrickson DS, Gordon RS.
Transport of fatty acids
Physiol Rev 38: 585-630, 1958.
Leblond CP, Walker BE.
Renewal of cell populations
Physiol Rev 36: 255-276, 1956.
Passmore R, Durnin JVGA.
Human energy expenditure
Physiol Rev 35: 801-840, 1955.
Lerner AB, Fitzpatrick TB.
Biochemistry of melanin formation
Physiol Rev 30: 91-126, 1950.
Journal of Neurophysiology
Discharge patterns and functional organization of mammalian retina
J Neurophysiol 16: 37-68, 1953.
Modality and topographic properties of single neurons of cats somatic sensory cortex
J Neurophysiol 20: 408-434, 1957.
Green JD, Arduini AA.
Hippocampal electrical activity in arousal
J Neurophysiol 17: 533-557, 1954.
Suppression of auditory nerve activity by stimulation of efferent fibers to cochlea
J Neurophysiol 19: 424-437, 1956.
Patton HD, Amassian VE.
Single-unit and multiple-unit analysis of cortical stage of pyramidal tract activation
J Neurophysiol 17: 345-363, 1954.
Larrabee MG, Posternak JM.
Selective action of anesthetics on synapses and axons in mammalian sympathetic ganglia
J Neurophysiol 15: 91-114, 1952.
Doty RW, Bosma JF.
Electromyographic analysis of reflex deglutition
J Neurophysiol 19: 44-60, 1956.
Araki T, Otani T.
Response of single motoneurons to direct stimulation in toads spinal cord
J Neurophysiol 18: 472-485, 1955.
Takeuchi A, Takeuchi N.
Active phase of frogs end-plate potential
J Neurophysiol 22: 395-411, 1959.
Hagbarth KE, Kerr DIB.
Central influences on spinal afferent conduction
J Neurophysiol 17: 295-307, 1954.
Journal of Applied Physiology
Brecher G, Cronkite EP.
Morphology and enumeration of human blood platelets
J Appl Physiol 3: 365-377, 1950.
Otis AB, McKerrow CB, Bartlett RA, Mead J, McIlroy MB, Selverstone NJ, Radford EP.
Mechanical factors in distribution of pulmonary ventilation
J Appl Physiol 8: 427-443, 1956.
Mead J, Whittenberger JL.
Physical properties of human lungs measured during spontaneous respiration
J Appl Physiol 5: 779-796, 1953.
Taylor HL, Buskirk E, Henschel A.
Maximal oxygen intake as an objective measure of cardio-respiratory performance
J Appl Physiol 8: 73-80, 1955.
Astrand PO, Ryhming I.
A nomogram for calculation of aerobic capacity (physical fitness) from pulse rate during submaximal work
J Appl Physiol 7: 218-221, 1954.
Severinghaus JW, Bradley AF.
Electrodes for blood PO2 and PCO2 determination
J Appl Physiol 13: 515-520, 1958.
Meier P, Zierler KL.
On the theory of the indicator-dilution method for measurement of blood flow and volume
J Appl Physiol 6: 731-744, 1954.
Roughton FJW, Forster RE.
Relative importance of diffusion and chemical reaction rates in determining rate of exchange of gases in the human lung, with special reference to true diffusing capacity of pulmonary membrane and volume of blood in the lung capillaries
J Appl Physiol 11: 290-302, 1957.
Otis AB, Fenn WO, Rahn H.
Mechanics of breathing in man
J Appl Physiol 2: 592-607, 1950.
Mead J, Collier C.
Relation of volume history of lungs to respiratory mechanics in anesthetized dogs
J Appl Physiol 14: 669-678, 1959.