In recognition of the Society’s 125th anniversary, and in acknowledgment of the critical role played by the APS journals in the Society’s legacy, Thomson Reuters, which produces the Journal Citation Reports database, including journal Impact Factors, was asked to identify the most highly cited articles since 1900. The Society therefore presents here the top ten cited articles for each of our journals for the following time periods: 1900-1924; 1925-1949; 1950-1959; 1960-1969; 1970-1979; 1980-1989; 1990-1999; and 2000-2011. [more]
Heyen DW, Weller JI, Ron M, Band M, Beever JE, Feldmesser E, Da Y, Wiggans GR, VanRaden PM, Lewin HA.
A genome scan for QTL influencing milk production and health traits in dairy cattle
Physiol Genomics 1: 165-175, 1999.
Davisson RL, Ding YM, Stec DE, Catterall JF, Sigmund CD.
Novel mechanism of hypertension revealed by cell-specific targeting of human angiotensinogen in transgenic mice
Physiol Genomics 1: 3-9, 1999.
Wolff GL, Roberts DW, Mountjoy KG.
Physiological consequences of ectopic agouti gene expression: the yellow obese mouse syndrome
Physiol Genomics 1: 151-163, 1999.
Kim J, Pelletier J.
Molecular genetics of chromosome translocations involving EWS and related family members
Physiol Genomics 1: 127-138, 1999.
Michiels EMC, Oussoren E, Van Groenigen M, Pauws E, Bossuyt PMM, Voute PA, Baas F.
Genes differentially expressed in medulloblastoma and fetal brain
Physiol Genomics 1: 83-91, 1999.
Halleck MS, Lawler JF, Blackshaw S, Gao L, Nagarajan P, Hacker C, Pyle S, Newman JT, Nakanishi Y, Ando H, Weinstock D, Williamson P, Schlegel RA.
Differential expression of putative transbilayer amphipath transporters
Physiol Genomics 1: 139-150, 1999.
Elgadi KM, Meguid RA, Qian M, Souba WW, Abcouwer SF.
Cloning and analysis of unique human glutaminase isoforms generated by tissue-specific alternative splicing
Physiol Genomics 1: 51-62, 1999.
Davia K, Hajjar RJ, Terracciano CMN, Kent NS, Ranu HK, O'Gara P, Rosenzweig A, Harding SE.
Functional alterations in adult rat myocytes after overexpression of phospholamban with use of adenovirus
Physiol Genomics 1: 41-50, 1999.
Strausberg RL, Austin MJF.
Functional genomics: technological challenges and opportunities
Physiol Genomics 1: 25-32, 1999.
Xue BZ, Wilkison WO, Mynatt RL, Moustaid N, Goldman M, Zemel MB.
The agouti gene product stimulates pancreatic beta-cell Ca2+ signaling and insulin release
Physiol Genomics 1: 11-19, 1999.
Warrington JA, Nair A, Mahadevappa M, Tsyganskaya M.
Comparison of human adult and fetal expression and identification of 535 housekeeping/maintenance genes
Physiol Genomics 2: 143-147, 2000.
Van Remmen H, Ikeno Y, Hamilton M, Pahlavani M, Wolf N, Thorpe SR, Alderson NL, Baynes JW, Epstein CJ, Huang TT, Nelson J, Strong R, Richardson A.
Life-long reduction in MnSOD activity results in increased DNA damage and higher incidence of cancer but does not accelerate aging
Physiol Genomics 16: 29-37, 2003.
Hsiao LL, Dangond F, Yoshida T, Hong R, Jensen RV, Misra J, Dillon W, Lee KF, Clark KE, Haverty P, Weng ZP, Mutter GL, Frosch MP, MacDonald ME, Milford EL, Crum CP, Bueno R, Pratt RE, Mahadevappa M, Warrington JA, Stephanopoulos G, Gullans SR.
A compendium of gene expression in normal human tissues
Physiol Genomics 7: 97-104, 2001.
Pastinen T, Sladek R, Gurd S, Sammak A, Ge B, Lepage P, Lavergne K, Villeneuve A, Gaudin T, Brandstrom H, Beck A, Verner A, Kingsley J, Harmsen E, Labuda D, Morgan K, Vohl MC, Naumova AK, Sinnett D, Hudson TJ.
A survey of genetic and epigenetic variation affecting human gene expression
Physiol Genomics 16: 184-193, 2004.
Stears RL, Getts RC, Gullans SR.
A novel, sensitive detection system for high-density microarrays using dendrimer technology
Physiol Genomics 3: 93-99, 2000.
Markert JM, Fuller CM, Gillespie GY, Bubien JK, McLean LA, Hong RL, Lee K, Gullans SR, Mapstone TB, Benos DJ.
Differential gene expression profiling in human brain tumors
Physiol Genomics 5: 21-33, 2001.
Butz GM, Davisson RL.
Long-term telemetric measurement of cardiovascular parameters in awake mice: a physiological genomics tool
Physiol Genomics 5: 89-97, 2001.
Chen BPC, Li YS, Zhao YH, Chen KD, Li S, Lao JM, Yuan SL, Shyy JYJ, Chien S.
DNA microarray analysis of gene expression in endothelial cells in response to 24-h shear stress
Physiol Genomics 7: 55-63, 2001.
Zhou XH, Krueger JG, Kao MCJ, Lee E, Du FH, Menter A, Wong WH, Bowcock AM.
Novel mechanisms of T-cell and dendritic cell activation revealed by profiling of psoriasis on the 63,100-element oligonucleotide array
Physiol Genomics 13: 69-78, 2003.
Tham DM, Martin-McNulty B, Wang YX, Wilson DW, Vergona R, Sullivan ME, Dole W, Rutledge JC.
Angiotensin II is associated with activation of NF-kappa B-mediated genes and downregulation of PPARs
Physiol Genomics 11: 21-30, 2002.