WEBINAR SERIES—Science of Aging—Aging and Bone Health

June 22, 2021
11 a.m. EDT

Osteoporosis is one of the most common degenerative diseases of aging. Half of adult women and one-quarter of adult men will develop an osteoporosis-related fracture. Current approaches for treating osteoporosis can lower the risk of fracture, but there is no cure. In this webinar, Joy Wu, MD, PhD of Stanford University in California, will review the pathophysiology of bone loss with aging, focusing on the imbalance between bone formation by osteoblasts and bone resorption by osteoclasts. She will discuss stem cell sources of osteoblasts, anabolic signaling pathways and targeting inflammation and senescence.

Key learning objectives include:

• describing how bone formation and resorption are coupled and regulate bone mass,
• exploring factors that contribute to aging-related bone loss, and
• discussing benefits and limitations of current osteoporosis therapies.

Presenter

Joy Wu, MD, PhD, directs a broad basic and translational research program that focuses on skeletal development and the bone marrow hematopoietic niche. Her laboratory is currently studying stem cell therapies for bone formation, and the prevention of cancer metastases to bone. She has been honored with awards from the NIH Director’s New Innovator Award, the Endocrine Society, the American Society for Bone and Mineral Research and the Mary Kay Foundation. Wu is committed to training the next generation of physician scientists, and serves as co-director of the Stanford Internal Medicine Translational Investigator Program.