WEBINAR SERIES—An Integrated Understanding of Pressure and Flow: An Essential Partnership

March 1, 2022
1 p.m. EST

A tightly controlled relationship between blood pressure and organ blood flow is vital for matching an organ’s metabolic needs to deliver oxygen and nutrients. However, the nature of the pressure-flow relationship is complex and is governed by multiple control systems, including local autoregulatory mechanisms at the level of the individual organ and neural and hormonal modulation.

To fully understand how pressure-flow relationships operate in health, and how they may be altered in pathological settings, it is essential to make direct, long-term assessments of blood pressure and blood flow under normal physiological conditions (i.e., in the conscious state).

In this presentation, Fiona McBryde, PhD, of the University of Auckland, New Zealand, will share insights from her studies of how the relationship between blood pressure and blood flow is altered in hypertension, and to consumer organs (such as the brain) and supply circulations (such as the mesenteric venous pool).

Key Learning Objectives Include:

• understanding the importance of assessing blood pressure and organ blood flow in tandem,
• appreciating some of the challenges in making studies physiologically and/or clinically relevant, and
• gaining insight into how the pressure-flow relationship can differ between end organs and under conditions of cardiovascular disease.

Speaker

Fiona McBryde, PhD, senior lecturer at the University of Auckland in New Zealand, is an integrative cardiovascular physiologist, with a particular focus in the relationships between autonomic activity, blood pressure and organ blood flow. Her recent research interests include static and dynamic pressure-flow relationships in the brain in hypertension and stroke, and the regulation of venous tone and compliance.