WEBINAR—Biomarker Analysis with Nanopore Technology

November 2, 2022
12 p.m. EDT

Watch on-demand

Nanopore readers are a relatively new technology in cell and molecular physiology. They allow researchers to investigate a wide range of phenomena involving DNA and RNA by monitoring ion currents and forces as molecules pass through a biological nanopore. Nanopore readers are widely used for the sequencing of nucleic acids, but can also allow the fingerprinting of protein biomarkers. In this webinar, Paolo Actis, PhD, of the University of Leeds in the U.K., will describe the development of a handheld nanopore-based device that detects the presence of protein biomarkers related to acute kidney injury (AKI) in biological fluids within minutes. Nanopore technology allows for the counting of biomarkers one at a time, as it is sensitive enough for a single molecule to pass through the nanopore. This is a key advantage over competing technologies that often require the detection of trillions of analytes before a signal can be processed. The program will present other applications of nanopore technology that enable the structural analysis of ribosomal complexes and amyloids and will emphasize how portable and easy-to use platforms and user interfaces will enable the widespread adoption of nanopore technology in research laboratories and clinical settings.

Speaker

Paolo Actis, PhD, is an associate professor of bionanotechnology in the School of Electronic and Electrical Engineering at the University of Leeds, in the U.K. He received a PhD in electrochemistry from the Grenoble Institute of Technology in France, and previously worked at NASA’s Ames Research Center in California and the University of California, Santa Cruz. Actis was also a consultant and project manager at Bio Nano Consulting.