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December 8, 2022
11 a.m. EST

Join Sarah Greising, PhD, as she discusses the current pathophysiologic understanding of remaining skeletal muscle following traumatic musculoskeletal injuries. 

Volumetric muscle loss (VML) injuries result in the abrupt loss of skeletal muscle fibers, causing chronic functional disability. This occurs in part due to limited muscle regeneration and vast co-morbidities. With a focus on clinically relevant outcome measurements for skeletal muscle function in small and large animal models of VML injury; this webinar will present various near-term interventions for the restoration of tissue function following complex injuries. Interventions evaluated will focus on regenerative rehabilitation approaches using regenerative pharmaceuticals to correct underlying muscle pathophysiology. 

Key Learning Objectives include: 

  • understanding the pathophysiologic limitations of volumetric muscle loss injuries, 
  • appreciating the importance and necessity of evaluating treatment strategies in large animal models of injury for translational purposes, 
  • understanding the tools used to evaluate in vivo torque, and 
  • understanding how data on a primary function of muscle can be transformative across species and fields. 

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Sarah Greising, PhD, is an associate professor at the University of Minnesota. Her research and labfocuses on conditions of skeletal muscle that have altered plasticity and/or limited to no regenerative potential, such as injury, aging and disease.

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