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May 15, 2024
11 a.m. EST

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The Davson Distinguished Lectureship is the Cell & Molecular Section’s highest award bestowed to a scientist who has made major and meritorious contributions to the scientific areas represented by the section in honor Hugh Davson (November 25, 1909–July 1996). Davson is well regarded for his work on ion transport and ocular fluids.

Shey-Shing Sheu, PhD, is the 2024 awardee. His talk focuses on the role of calcium ions in regulating mitochondria bioenergetics and reactive oxygen species dynamics and translates these basic mechanisms to the pathogenesis of cardiac arrhythmias and heart failure.

Key Learning Objectives Include:

  • appreciating the importance of mitochondrial bioenergetics in controlling cardiac muscle cell function,
  • comprehending the mechanism of crosstalk calcium ion signaling between the sarcoplasmic reticulum and mitochondria and its functional implications in the heart, and
  • understanding the multifaceted roles of mitochondrial dynamics and permeability transition pores in cell physiology and pathology.
Lecturer

Hugh Davson DL - Shey-Shing Sheu 200x200Shey-Shing Sheu, PhD
William Wikoff Smith Endowed Chair Professor of Cardiovascular Research and associate director of the Center for Translational Medicine at Thomas Jefferson University

Shey-Shing Sheu, PhD, is the William Wikoff Smith Endowed Chair Professor of Cardiovascular Research at the Center for Translational Medicine at Thomas Jefferson University. Sheu did his PhD research in the late Harry Fozzard’s lab at the University of Chicago. He then joined the lab of Mordecai Blaustein, MD, and Jonathan Lederer, MD, PhD, as a research assistant professor at the University of Maryland. He was a full professor at the University of Rochester before relocating to Thomas Jefferson University in Philadelphia, where he has resided since 2011.

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