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Circadian clocks—24-hour molecular timers that exist in virtually all cells in the body—function to support cell, tissue and systemic homeostasis. Preclinical and clinical data support the role of circadian clocks in skeletal muscle homeostasis through management of pathways important for maintenance of muscle strength and metabolic flexibility. Hear about research that demonstrates the valuable role skeletal muscle clocks play as a key modulator of healthy adaptations to endurance exercise, changes in muscle clocks and muscle health as important contributors to systemic, nonmuscle tissue health. 

What You’ll Learn 

  • Defining molecular organization and logic of circadian clocks.
  • Delineating mechanisms by which circadian clocks regulate skeletal muscle strength and metabolism.
  • Examining the interaction between skeletal muscle clocks and endurance exercise adaptations.
  • Interpreting circadian modulation as a mechanistic variable in experimental and translational study design.

Who Should Attend 

  • Muscle biologists.
  • Sleep researchers.

Speaker

Karyn Esser, PhD, Professor
University of Florida 

Karyn Esser, PhD, is a professor and chair of Department of Physiology and Aging at the University of Florida. Her lab pioneered research on the role of circadian rhythm in skeletal muscle homeostasis and systemic health and their role in maintaining strength and metabolic flexibility. Esser’s work examines muscle clocks as components of exercise responses, aging and chronic diseases. 

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