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Teens and young adults are increasingly using electronic cigarettes, but little is known about the long-term cardiopulmonary health effects of these nicotine delivery devices.

During this webinar, Jason Gardner, PhD, of Louisiana State University Health Sciences Center, will present his latest findings using a mouse model of chronic inhaled nicotine exposure. Post-exposure to nicotine caused mice to develop pulmonary hypertension and right ventricular remodeling, a phenomenon that is prevented using the angiotensin II type I receptor blocker losartan. Gardner will discuss the details of this work and how the renin-angiotensin system plays a key role in pulmonary hypertension and right ventricular remodeling. In addition, he will expand upon the current research with new, unpublished findings.

Key learning objectives include:

  • effects of chronically inhaled nicotine on the heart,
  • effects of chronic nicotine exposure on systemic blood pressure and left heart function, and
  • interplay of nicotine and the renin-angiotensin system in pulmonary hypertension pathology.

Speaker

Jason Gardner, PhDJason Gardner, PhD, is a professor of physiology at Louisiana State University Health Sciences Center in New Orleans. His active research projects include the cardiac effects of chronic inhaled nicotine, prenatal alcohol exposure and cardiac dysfunction, and the mechanisms of alcoholic cardiomyopathy.

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