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January 23, 2024
11 a.m. EST

Watch on-demand

Brown adipose tissue (BAT; or “brown fat”) is recognized as a “good” fat with protective effects against cardiometabolic diseases. The best-known function of BAT is thermogenesis by the action of mitochondrial uncoupling protein 1 (UCP1). For many years, UCP1 was considered to be the sole protein responsible for non-shivering thermogenesis (the process of heat production) in mammals. As such, the metabolic benefit associated with active BAT was thought to be through enhancing UCP1-mediated thermogenesis. However, recent studies identified UCP1-independent pathways that control energy homeostasis. This webinar will discuss the current standing of UCP1-independent mechanisms.

Key learning objectives include:

  • understanding what brown fat is, 
  • how UCP1 and UCP1-independent pathways control energy metabolism, and
  • new insights into the role of brown fat in metabolic disease.
Speaker

Shingo Kajimura 200x200Shingo Kajimura, PhD ScD
Professor, Harvard Medical School, Beth Israel Deaconess Medical Center

Shingo Kajimura, PhD, ScD, is a professor of medicine at Harvard Medical School and Beth Israel Deaconess Medical Center in Boston and an investigator at Howard Hughes Medical Institute in Chevy Chase, Maryland. His research focuses on understanding the molecular basis of bioenergetics, with an emphasis on the role of brown fat in energy homeostasis. Kajimura’s research led to the discovery of new pathways controlling thermogenesis and energy homeostasis.

Sponsored by:
Columbus-Instruments-New-2023

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