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New study incorporates effects of daily activities, finds greater heat strain

Craig Crandall, PhD

Rockville, Md. (September 26, 2023)—Under conditions designed to better mirror real-world conditions, a new study finds that adults 65 and older are affected more by heatwave-like temperatures than previously reported. The study is published ahead of print in the Journal of Applied Physiology. It was chosen as an APSselect article for September.

“The extent of thermal strain reported herein more accurately represents what would occur during actual heatwave conditions.”

The research team introduced intermittent bouts of light activity into the study to account for the effects of daily living, such as cooking, cleaning or carrying groceries. They also closely monitored the volunteers’ hydration levels to remove the cofounding factor of dehydration from the results.

In the study, two groups of healthy adults—one between ages 18 and 39 and the other age 65 and older—completed two separate experimental heat simulations. Participants first rested for an hour in a temperate environment (~72° F, 40% humidity) while researchers collected baseline data. The adults then entered a temperature- and humidity-controlled environmental chamber for three hours. While in the chamber, the participants performed seven five-minute rounds of either cycling or walking at a pace that replicates the light physical activity associated with daily living. For one of the simulations, the chamber was set to about 116° F and 15% humidity to emulate the conditions of the 2018 Los Angeles heatwave. The other was set to about 106° F and 40% humidity to emulate the 1995 Chicago heatwave.

While the older adults had similar skin blood flow and sweat rates as the younger group, they also had “an approximately twofold greater increase” in core body temperature. Accounting for this greater change in core temperature reveals that the older adults’ sweat and skin blood flow responses did not respond adequately to maintain a healthy body temperature.

This method of mimicking daily life during a heatwave “resulted in greater thermal strain than what has been previously reported in the literature during similar heat exposures,” researchers report.

Read the full article, “Age alters the thermoregulatory responses to extreme heat exposure with accompanying activities of daily living,” published ahead of print in the Journal of Applied Physiology. It is highlighted as one of this month’s “best of the best” as part of the American Physiological Society’s APSselect program. Read all of this month’s selected research articles.

NOTE TO JOURNALISTS: To schedule an interview with a member of the research team, please contact APS Media Relations or call 301.634.7314. Find more research highlights in our Newsroom.

Physiology is a broad area of scientific inquiry that focuses on how molecules, cells, tissues and organs function in health and disease. The American Physiological Society connects a global, multidisciplinary community of more than 10,000 biomedical scientists and educators as part of its mission to advance scientific discovery, understand life and improve health. The Society drives collaboration and spotlights scientific discoveries through its 16 scholarly journals and programming that support researchers and educators in their work.

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